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PRODID:-//Department of Theoretical Physics - ECPv6.5.1.5//NONSGML v1.0//EN
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X-WR-CALNAME:Department of Theoretical Physics
X-ORIGINAL-URL:https://web-f1.ijs.si
X-WR-CALDESC:Events for Department of Theoretical Physics
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BEGIN:VTIMEZONE
TZID:Europe/Ljubljana
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20260329T010000
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BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20261025T010000
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BEGIN:VEVENT
DTSTART;TZID=Europe/Ljubljana:20260115T140000
DTEND;TZID=Europe/Ljubljana:20260115T150000
DTSTAMP:20260422T031623
CREATED:20251002T094354Z
LAST-MODIFIED:20260115T133207Z
UID:74451-1768485600-1768489200@web-f1.ijs.si
SUMMARY:Anže Božič\, "Some electrostatics of proteins and capsids"
DESCRIPTION:https://indico.ijs.si/event/3107/
URL:https://web-f1.ijs.si/event/veronika-bukina-tba-3/
LOCATION:A/1-106 – Seminarska soba fizike (F5) (Jamova)
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BEGIN:VEVENT
DTSTART;TZID=Europe/Ljubljana:20260122T110000
DTEND;TZID=Europe/Ljubljana:20260122T120000
DTSTAMP:20260422T031623
CREATED:20251202T145925Z
LAST-MODIFIED:20260122T102113Z
UID:80466-1769079600-1769083200@web-f1.ijs.si
SUMMARY:Sofie Martins: Computing cross-sections from the lattice — A recent shift in lattice thinking paradigms?
DESCRIPTION:Extracting scattering amplitudes — and consequently cross-sections — from non-perturbative lattice techniques has seen significant advances in recent years. People have so far relied on Luescher’s method\, which relates Euclidean finite-volume effects of lattice correlators to infinite-volume Minkowskian Scattering Amplitudes. While this method has achieved enormous success\, its limitations are somewhat discouraging: the invalidity beyond the inelastic threshold limits predictions to lower-point exclusive particle-scattering processes. New lattice methods by Hansen/Bulava and Tantalo/Patella have addressed this by rethinking the computation of scattering amplitudes on the lattice in terms of spectral densities\, which we can extract from large lattices with increasing precision. These methods allow the examination of exclusive processes even above the inelastic threshold and are consequently an invaluable tool for comparing and complementing perturbative computations with lattice results.I will present preliminary results for the Hansen/Bulava method in a particularly tractable theory that models a gauge-invariant implementation of the electroweak sector.\nhttps://indico.ijs.si/event/3407/
URL:https://web-f1.ijs.si/event/sofie-martins-tba/
LOCATION:A/1-106 – Seminarska soba fizike (F5)
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=Europe/Ljubljana:20260122T130000
DTEND;TZID=Europe/Ljubljana:20260122T140000
DTSTAMP:20260422T031623
CREATED:20251218T142803Z
LAST-MODIFIED:20260122T115550Z
UID:82104-1769086800-1769090400@web-f1.ijs.si
SUMMARY:Leah Rank\, "Hollow microgels: From single particle characterisation to bulk behaviour"
DESCRIPTION:Hollow microgels are elastic polymer shells easily realisable in experiments. Recent works have shown the emergence of buckling events in dilute hollow microgels under the effect of an added osmotic pressure. Here\, we perform large-scale simulations to show that these microgels at high enough packing fractions undergo spontaneous symmetry-breaking deformations ranging from single large dents to multiple indentations\, even in the absence of any externally applied stress. This self-induced buckling phenomenon is thus solely driven by interparticle crowding. We construct a phase diagram inspired by vesicle shape theories\, mapping local curvature metrics as a function of the reduced volume\, to quantify these findings\, and we also propose ways to observe the occurrence of buckling in experiments. The present results thus rationalize the deformations occurring in suspensions of micro- and nano-scale elastic shells\, offering a synthetic analogue to biological ones and allowing direct control on buckling instabilities for potential applications. Beyond materials design\, these insights may also help to describe shape regulation in natural systems such as cells and vesicles\, where similar deformations are observed.\nhttps://indico.ijs.si/event/3442/
URL:https://web-f1.ijs.si/event/lear-rank-tba/
LOCATION:A/1-106 – Seminarska soba fizike (F5) (Jamova)
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BEGIN:VEVENT
DTSTART;TZID=Europe/Ljubljana:20260129T141500
DTEND;TZID=Europe/Ljubljana:20260129T151500
DTSTAMP:20260422T031623
CREATED:20260125T214828Z
LAST-MODIFIED:20260129T140532Z
UID:85791-1769696100-1769699700@web-f1.ijs.si
SUMMARY:Urban Bren\, "Biomolecular Simulations as a Useful Tool in a Fight against Cancer"
DESCRIPTION:The lecture focuses on food safety in the context of chemical carcinogens\, which are often present in raw or thermally processed foods and\, after initial activation\, alkylate DNA\, usually guanine at position N7. Recently\, important biochemical phenomena have been discovered\, such as DNA catalysis of genetic damage\, biomolecular cooperativity\, in-vivo persistence of DNA adducts and the mutational propensity of DNA polymerases\, which still lack an adequate mechanistic explanation. To elucidate their molecular basis\, we used a range of state-of-the-art computer simulation techniques in conjunction with free energy calculations and the corresponding thermodynamic cycles. Since microwaves have been shown to catalyze numerous chemical reactions\, we are concerned about the possibility of increased reactivity of chemical carcinogens\, which also offers an explanation for why microwaves were recently classified as potentially carcinogenic by the World Health Organization. Therefore\, we considered the reactions between chemical carcinogens and DNA in the context of our recently proposed physical mechanism of microwave catalysis\, based on rotationally excited polar reaction species. Moreover\, microwave irradiation has been shown to accelerate peptide misfolding and aggregation\, processes that are generally associated with the occurrence of certain cancer types\, e.g. amyloidosis. The microwave-irradiated solution thus through rotationally excited water molecules presents a less polar and less protic medium\, thereby accelerating the harmful misfolding of peptides and their aggregation. We tested this hypothesis using molecular dynamics simulations in combination with a dedicated integrator\, which is capable of efficiently decoupling individual degrees of freedom of water molecules and connecting them with the corresponding thermostats. Furthermore\, we have used quantum chemical approaches to study the reactions between chemical carcinogens and polyphenols\, secondary metabolites from fruits and vegetables. As a general rule for preventing DNA damage\, a chemical carcinogen should react faster with a polyphenol scavenger than with DNA. Since the activation free energy represents a direct measure of reactivity\, the reaction of a chemical carcinogen with a scavenger should have a lower activation barrier than the competitive alkylation of DNA. The long-term goal is to discover natural compounds or their mixtures with high antigenotoxic activities that could\, after optimization\, serve as functional dietary supplements and thus significantly contribute to cancer prevention.\nhttps://indico.ijs.si/event/3605/
URL:https://web-f1.ijs.si/event/urban-bren-biomolecular-simulations-as-a-useful-tool-in-a-fight-against-cancer/
LOCATION:Seminar room of physics (106) (IJS)
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BEGIN:VEVENT
DTSTART;TZID=Europe/Ljubljana:20260130T103000
DTEND;TZID=Europe/Ljubljana:20260130T113000
DTSTAMP:20260422T031623
CREATED:20260128T140107Z
LAST-MODIFIED:20260130T101556Z
UID:86085-1769769000-1769772600@web-f1.ijs.si
SUMMARY:Aleks Smolkovič - Fast and differentiable EFT likelihoods
DESCRIPTION:The Standard Model Effective Field Theory (SMEFT) has proven to be a valuable framework for studying a broad class of models beyond the SM containing heavy degrees of freedom. The phenomenology of SMEFT can be developed systematically\, incorporating essential effects such as Renormalization Group evolution and matching onto subsequent low-energy Weak Effective Field Theories (WET)\, enabling predictions for a wide range of observables. A likelihood function for the SMEFT that compares theory predictions to experimental data can be employed to identify patterns of deviation from SM predictions\, but also to study the phenomenology of any specific model that can be matched onto SMEFT. In this talk\, we present a new open source Python package jelli – JAX-based EFT likelihoods\, which provides fast and analytically differentiable generic likelihood functions for EFT studies. We discuss a major new version of smelli – a SMEFT likelihood\, which incorporates a large number of observables\, ranging from quark and lepton flavor physics\, to Higgs physics\, electroweak precision observables\, beta decays\, and high-mass Drell-Yan tails. Running on the jelli backend\, it provides a global flavorful likelihood function for the SMEFT\, WET\, and for new physics models\, with no assumptions on the flavor structure. Thanks to its numerical efficiency and differentiability\, it opens up new avenues in exploring BSM parameter spaces.\nhttps://indico.ijs.si/event/3638/
URL:https://web-f1.ijs.si/event/aleks-smolkovic-fast-and-differentiable-eft-likelihoods/
LOCATION:F1 tea room
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