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[Biophysics seminar] Clement Zankoc: “Active Instability and Nonlinear Dynamics of Cell-Cell Junctions”
7. December, 2021 at 15:00 - 16:00
|Active cell-junction remodeling is important for tissue morphogenesis, yet its underlying physics is not understood. We study a mechanical model that describes junctions as dynamic active force dipoles. Their instability can trigger cell intercalations by a critical collapse. Nonlinearities in tissue’s elastic response can stabilize the collapse either by a limit cycle or condensation of junction lengths at cusps of the energy landscape. Furthermore, active junction networks undergo collective instability to drive active in-plane ordering or develop a limit cycle of collective oscillations, which extends over regions of the energy landscape corresponding to distinct network topologies.|
|The meeting will take place online via Zoom:
Meeting ID: 833 0750 1179