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[Biophysics seminar] Gregor Posnjak: “From DNA origami to photonic crystals”
1. March, 2022 at 13:00 - 14:00
| The idea of using the predictable base pairing of DNA nucleobases for programmable assembly on the nanoscale dates back to the 1980s when the recently deceased Ned Seeman had the idea of using it to crystalize proteins on a DNA-based lattice for their structure determination with x-ray crystallography. After the first successful DNA nanostructures in the 1990s, the real boom came after 2006 when the concept of DNA origami was introduced. The use of a long DNA scaffold strand in combination with short staple strands eliminated many of the short-comings of the earlier approaches and enabled robust programmable assembly with resolution on the order of nanometers.
In the first part of the talk I will introduce the concept of DNA origami and give a short review of the various structures and super-structures that were developed and their applications in drug delivery, biophysics, super-resolution microscopy, sensing and plasmonics. In the second part I will shortly introduce photonic crystals as motivation for my work and then present a DNA-origami based self-assembled diamond lattice, which we will use as a template for realization of visible spectrum photonic crystals. |
| The meeting will take place online via Zoom:
Meeting ID: 833 0750 1179 Passcode: bio |