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[Biophysics seminar] Jan Rozman: “Shape-tension coupling produces nematic order in an epithelium vertex model”

10. January, 2023 at 14:00

We study the vertex model for epithelial tissue mechanics extended to include coupling between the cell shapes and tensions in cell-cell junctions. This coupling represents an active force which drives the system out of equilibrium and leads to the formation of nematic order interspersed with prominent, long-lived +1 defects. The defects in the nematic ordering are coupled to the shape of the cell tiling, affecting cell areas and coordinations. This intricate interplay between cell shape, size, and coordination provides a possible mechanism by which tissues could spontaneously develop long-range polarity through local mechanical forces without resorting to long-range chemical patterning.
The seminar will take place in the tearoom of the F1 department.

Details

Date:
10. January, 2023
Time:
14:00

Venue

F1 tearoom