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[Biophysics seminar] Maria Pedrosa Bustos: “Langmuir monolayers as membrane models to study anticancer drugs”
10. November, 2022 at 14:00 - 15:00
| When designing novel anticancer drugs, it is crucial to analyze how they interact with cell membranes. For this purpose, Langmuir monolayers have been widely used to mimic half of a cell membrane under controlled conditions. In this study, healthy and tumor cell membranes are emulated using different mixtures of phospholipids and cholesterol. Their interaction with a model anticancer drug (curcumin) is analyzed experimentally by means of a Langmuir through. These studies are complemented by molecular dynamics simulations, which offer additional molecular-level insight into the drug-monolayer interactions. |
The meeting will take place in the tearoom of the F1 department.
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