Electrostatic interactions play a key role in the behavior of soft and biological matter, yet their complexity increases when particle charge distributions are inhomogeneous. Dr. Anže Božič and his collaborators from FMF, University of Padova, and TU Wien recently published their work “Anisotropic DLVO-like interaction for charge patchiness in colloids and proteins” in Nature Communications, where they present a unified theoretical framework that bridges different electrostatic models to accurately and efficiently describe interactions between inhomogeneously charged particles such as colloids and proteins.